Topotecan


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290 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 PGP - PGP Canis lupus familiaris 610926 223 1
2 ATP binding cassette subfamily G member 2 Q38JL0_CANLF ABCG2 Canis lupus familiaris 478472 141 4
3 DNA topoisomerase I F1PUE0_CANLF TOP1 Canis lupus familiaris 477229 5 2
4 ATP binding cassette subfamily C member 2 Q9GK09_CANLF ABCC2 Canis lupus familiaris 403632 115 1
5 ATP binding cassette subfamily B member 1 Q4PLA8_CANLF ABCB1 Canis lupus familiaris 403879 180 1
6 Cyp6d2 CP6D2_DROME Cyp6d2 Drosophila melanogaster 37594 2 1
7 sticky Q9VTY8_DROME sti Drosophila melanogaster 39429 81 1
8 Topoisomerase 1 TOP1_DROME Top1 Drosophila melanogaster 32458 6 1
9 ATP binding cassette subfamily G member 2 F6Q6E8_HORSE ABCG2 Equus caballus 100034164 1 1
10 vascular endothelial growth factor A VEGFA_CHICK VEGFA Gallus gallus 395909 121 1
11 interferon gamma IFNG_HUMAN IFNG Homo sapiens 3458 3371 2
12 mucin 16, cell surface associated MUC16_HUMAN MUC16 Homo sapiens 94025 408 7
13 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_HUMAN ABCG2 Homo sapiens 9429 1370 116
14 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 2
15 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 9
16 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 38
17 microRNA 21 - MIR21 Homo sapiens 406991 733 2
18 SCLC1 - SCLC1 Homo sapiens 7864 68 10
19 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 5
20 H3 histone pseudogene 16 - H3P16 Homo sapiens 644914 2095 3
21 colony stimulating factor 2 CSF2_HUMAN CSF2 Homo sapiens 1437 2088 5
22 ATP binding cassette subfamily B member 6 (Langereis blood group) ABCB6_HUMAN ABCB6 Homo sapiens 10058 793 5
23 phosphoglycolate phosphatase PGP_HUMAN PGP Homo sapiens 283871 1342 5
24 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 5
25 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 5
26 checkpoint kinase 1 CHK1_HUMAN CHEK1 Homo sapiens 1111 648 5
27 hypoxia inducible factor 1 subunit alpha HIF1A_HUMAN HIF1A Homo sapiens 3091 2152 19
28 metallothionein 1E MT1E_HUMAN MT1E Homo sapiens 4493 133 4
29 H2A.X variant histone H2AX_HUMAN H2AX Homo sapiens 3014 412 8
30 RAD51 recombinase RAD51_HUMAN RAD51 Homo sapiens 5888 537 2
31 tyrosyl-DNA phosphodiesterase 1 TYDP1_HUMAN TDP1 Homo sapiens 55775 208 12
32 DNA topoisomerase I TOP1_HUMAN TOP1 Homo sapiens 7150 98 15
33 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 6
34 CD34 molecule CD34_HUMAN CD34 Homo sapiens 947 1218 4
35 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 6
36 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 11
37 MYCN proto-oncogene, bHLH transcription factor MYCN_HUMAN MYCN Homo sapiens 4613 374 4
38 chromobox 8 CBX8_HUMAN CBX8 Homo sapiens 57332 830 3
39 proprotein convertase subtilisin/kexin type 5 PCSK5_HUMAN PCSK5 Homo sapiens 5125 122 3
40 BH3 interacting domain death agonist BID_HUMAN BID Homo sapiens 637 1130 3
41 checkpoint kinase 2 CHK2_HUMAN CHEK2 Homo sapiens 11200 417 3
42 Fas ligand TNFL6_HUMAN FASLG Homo sapiens 356 783 3
43 schlafen family member 11 SLN11_HUMAN SLFN11 Homo sapiens 91607 41 3
44 TNF receptor superfamily member 10b TR10B_HUMAN TNFRSF10B Homo sapiens 8795 608 3
45 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 3
46 RB transcriptional corepressor 1 RB_HUMAN RB1 Homo sapiens 5925 809 3
47 TNF superfamily member 10 TNF10_HUMAN TNFSF10 Homo sapiens 8743 1439 3
48 annexin A5 ANXA5_HUMAN ANXA5 Homo sapiens 308 1785 3
49 Fas cell surface death receptor TNR6_HUMAN FAS Homo sapiens 355 474 3
50 BRCA1 DNA repair associated BRCA1_HUMAN BRCA1 Homo sapiens 672 696 6